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Core Faculty

Barbara Doucet, PhD

Doug Paddon-Jones PhD

Doug Paddon-Jones PhD
Associate Professor
Department of Physical Therapy


301 University Boulevard
Galveston, TX 77555-0912
Phone: (409) 772-3068
Fax: (409) 747-1613
Email: djpaddon@utmb.edu

Research Areas

Muscle metabolism, Protein synthesis



Queensland University of Technology, Australia

Medical Imaging

Dip. App. Sc.


University of Queensland, Australia




University of Queensland, Australia

Human Movement

BSc (Hons)

1996 Ball State University, Indiana Exercise Physiology MS
1999 University of Queensland, Australia Human Movement PhD
Current Funding

NNJ08ZSA002N NSBRI Paddon-Jones (PI) 06/09-06/13 An integrated low-volume nutritional countermeasure to maintain muscle mass and function during space exploration The goal of this project is to determine if enriching daily meals with a low-volume leucine supplement will reduce the deleterious effects of microgravity on skeletal muscle Role: PI

Past Funding

Role: PI
Industry Paddon-Jones (PI) 06/09 – 06/11

National Cattlemen’s Beef Association Protein Needs for Optimal Meal Response
Our goal is to determine the amount of protein required to maximize muscle growth and satiety
Role: PI

UT TeleCampus Utsey (PI) 08/08 -08/09
Pharmacology and Imaging: Two online courses for DPT students and practicing physical therapist
This grant provides funds for the development and delivery of two online graduate-level courses
Role: Co-I/Course Instructor
RO1 Sheffield-Moore (PI) 05/08-05/012 09/01/03 - 5/31/08

Nutrition and anabolic interventions in cancer cachexia
The goal of this proposal is to determine the mechanisms underlying the cancer-induced loss of skeletal muscle protein, and examine whether 3 months of targeted nutritional and hormonal interventions can overcome the influence of and NF-κB.
Role: Co-Iamuscle proteolytic factors such as TNF-

Inst. for Translational Science Volpi (PI) 01/09-01/11
Multidisciplinary Translational Team Grant: Muscle Aging and Sarcopenia
The goal of this MTT is to develop and test interventions to improve function and independence in older adults

UTMB Brasier (PI) 05/08-05/10
Claude D. Pepper Older Americans Independence Center Serum Biomarkers in Inactivity-Induced Sarcopenia
The goal of this study is to identify biomarkers associated with increased muscle breakdown and develop clinical studies for development of intervention strategies
Role: Co-I

UTMB Doucet (PI) 05/08-05/10
Claude D. Pepper Older Americans Independence Center Electrical Stimulation and Nutritional Support in Hospitalized Elders
The goal of this study is reduce the loss of muscle mass and functional capacity in hospitalized elders
Role: Co-I/Mentor

UTMB McGaugh (PI) 05/08-05/10
Claude D. Pepper Older Americans Independence Center Effects of nutrition and intensive rehabilitation on recovery after hip fracture
The goal of this study is to reduce the loss of muscle mass and strength that occur acutely following hip fracture, in an effort to facilitate longer-term functional recovery and independence
Role: Co-I/Mentor

RO1 AG021539-03 Sheffield-Moore (PI) 09/03/05/09 09/01/03 - 5/31/08
Muscle Perfusion and Protein Metabolism in Elderly and Young The goal of this proposal is to determine the effects of increased muscle perfusion on muscle protein synthesis in elderly, either through aerobic exercise or peripheral vasodilation and amino acids
Role: Co-I

P30 AG02832 Goodwin (PI) 06/05-04/10
NIH: Development Core
The major goals of this center grant was to conduct basic and clinical research on ways for elderly Americans to lead a more independent life
The center is focused on the effect of aging on skeletal muscle and protein metabolism, and in particular the effects of nutrition and androgens
Role: Faculty recipient

Select Publications

Durham WJ, Casperson SL, Dillon EL, Keske MA, Paddon-Jones D, Sanford AP, Hickner RC, Grady JJ, Sheffield-Moore M. Age-related anabolic resistance after endurance-type exercise in healthy humans. The Federation of American Societies for Experimental Biology Journal. 2010 Jun 14. PMID: 20547663

English KL, Paddon-Jones D. Protecting muscle mass and function in older adults during bed rest. Current Options in Clinical Nutrition Metabolism Care. 2010 Jan;13(1):34-9. Review.PMID: 19898232

Ferrando AA, Paddon-Jones D, Hays NP, Kortebein P, Ronsen O, Williams RH, McComb A, Symons TB, Wolfe RR, Evans W. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clinical Nutrition. 2010 Feb;29(1):18-23.PMID: